Our studies showed that there were no significant differences in the frequency of UGT1A1*6 between GRHF (32.4%) and CTRL, HBV (29.6%) and CTRL (26.5%), GFHF (34.3%) and HBV, GRHF and HBV, or GRHF and GFHF, suggesting that this variant was not associated with cholelithiasis observed in HBV-related liver failure. Here, UGT1A1 is linked to liver failure.