FLNB and hereditary leiomyomatosis and renal cell cancer: In this study, compared to tumors formed by RENCA parental cells, harvested Fh1-KO tumors displayed altered morphology characterized by enlarged cells with large nuclei, prominent eosinophilic nucleoli, and perinucleolar halos (Figure 3C), similar to the characteristic features of HLRCC tumors [21].