In support of our findings Dvl has been implicated in oncogenesis and is overexpressed in prostate cancer, non-small cell lung cancer, mesothelioma and colon cancer; its upregulation has been implicated to be correlated with activation of Wnt/β-catenin signaling and an increased risk of malignant transformation [14–17]. This evidence concerns the gene DVL1 and prostate carcinoma.