GSDME and neoplasm: The other 37 genes were enriched in the tumor group, including BAK1, BAX, CASP3, CASP4, CHMP2A, CHMP2B, CHMP3, CHMP4A, CHMP4B, CHMP4C, CHMP6, CHMP7, CYCS, GSDMD, GSDME, HMGB1, IL1A, IRF2, TP53, TP63, CASP6, CASP8, CASP9, GPX4, GSDMA, GSDMB, GSDMC, NLRP1, NLRP7, NOD1, NOD2, PJVK, PLCG1, PRKACA, PYCARD, SCAF11, and TIRAP (Fig. 2A).