POSTN and lung cancer: Moreover, we identified a subtype of ECs that expressed marker genes of activated post-capillary venules (PCV; EC6; POSTN) (Fig. 1d; Supplementary Fig. 1a), previously identified in EC taxonomies of lung cancer and laser-induced choroid neovascularization (CNV)14,19 and suggested to represent the vessel type from which neovessels originate14.