To further investigate the relationship between FBXO22 and cervical neoplastic progression, formalin-fixed paraffin-embedded cervical tissues, including 20 normal cervical epithelium (NC), 20 cervical squamous intraepithelial lesion (SIL), and 20 cervical squamous cell cancer (SCC), were utilized to analyze the expression of FBXO22 protein by IHC analysis. The gene discussed is FBXO22; the disease is squamous cell intraepithelial neoplasia.