TGFBI and neoplasm: We performed immunofluorescence staining of TGFBI, representing the expression of p-EMT program, along with the SBC marker TBXT. This experiment revealed a population of SBC cells with a highly expressed p-EMT pattern, characterized by TGFBI expression and cell localization to the leading edge of the tumor in close apposition to the surrounding stroma (Fig. 5c).