Although different fragments of NDRG1-OT1 via recruiting distinct proteins had different effects on NDRG1 transcription in MCF-7 breast cancer cells under hypoxia [30], we discovered that NDRG1-OT1 was almost always located in a cytoplasmic fraction in MDA-MB-231 cells under both normoxia and hypoxia, which provides ample opportunity for lncRNA-miRNA interaction (Fig. 4A, B). The gene discussed is NDRG1; the disease is breast carcinoma.