Mice heterozygous for CaMKIIα (CaMKIIα Hets) have problems with working memory, increased anxiety, and aggressiveness, characteristic of schizophrenia (Yamasaki et al., 2008; Hasegawa et al., 2009; Matsuo et al., 2009; Chen et al., 1994). This evidence concerns the gene CAMK2A and Anxiety.