Analysis by LC-MS/MS identified more than 600 Lmo2-interacting molecules in physiological LPs, including the previously reported components of Lmo2 complexes in hematological cancer cell lines, Lyl1, Tal1, Ldb1, Tcf12, Tcf3, and Cbfa2t3 (also known as ETO2 or MTG16) (Fig. 1B and Table S1) (32, 33). This evidence concerns the gene TCF3 and hematopoietic and lymphoid cell neoplasm.