As for biochemical investigations on admission, severe dengue patients were shown to have significantly higher levels of urea (median 5.50; IQR: 3.30–9.30), creatinine (median 87; IQR: 63–151), ALT (median 144; IQR: 46–527), AST (median 300; IQR: 86–1159), CK (median 216; IQR: 98–620) and LDH (median 659; IQR: 380–1433) and significantly lower serum albumin levels (median 34; IQR: 30–38; p<0.0001) compared to non-severe dengue patients. This evidence concerns the gene ALB and dengue disease.