Compared with moderate-to-severe stroke, patients with mild stroke have lower hs-CRP levels [2.43 (1.09-5.74) vs. 1.50 (0.69-3.45, P<0.001], and associated with poor functional outcome (OR=3.149, 95% CI=1.669-5.940, P<0.001). The gene discussed is MAP3K14; the disease is Stroke.