Most notably, however, we found that our polyclonal FSH-blocking antibody, which shares the target epitope with MS-Hu6 (Zhu et al., 2012a; Gera et al., 2020), prevented the AD-like phenotype induced upon ovariectomy (Xiong et al., 2022)—providing a clear avenue for further exploration of the effects of MS-Hu6 in models of AD. Here, BRD2 is linked to Alzheimer disease.