Other pre‐existing factors for DAOSD include severe AD,17, 35, 39, 46 the presence of facial12 or eyelid42 eczema, a history of food allergy,42 a family history of atopy,17 and elevated baseline levels of IgE,35, 36, 42 serum thymus and activation‐regulated chemokine (TARC)35, 36 or blood eosinophil counts.36, 42. This evidence concerns the gene IGHE and Eczematoid dermatitis.