IGHE and Alzheimer disease: Other pre‐existing factors for DAOSD include severe AD,17, 35, 39, 46 the presence of facial12 or eyelid42 eczema, a history of food allergy,42 a family history of atopy,17 and elevated baseline levels of IgE,35, 36, 42 serum thymus and activation‐regulated chemokine (TARC)35, 36 or blood eosinophil counts.36, 42