BRD2 and Testicular atrophy: These results were in good accordance of Abdel Moneim [20] who showed that CCl4 administration caused testicular atrophy, decrease in testosterone and gonadotropins (FSH and LH) in male rat, and stated that P. peruviana fruit could increase testosterone, FSH and LH levels through direct effects on the central nervous system and gonadal tissues or their effects on hypothalamus–pituitary–testis axis.