Central cytokines regulating immune responses in RA include interferons (IFNs), Interleukin-1 (IL-1), IL-6, IL-7, IL-12, IL-15, IL-17, IL-23, tumor necrosis factor-α (TNF) and granulocyte-macrophage colony-stimulating factor [2]. The gene discussed is IL7; the disease is rheumatoid arthritis.