HPSE2 and Ochoa syndrome: Several monogenic causes of other congenital bladder outflow obstruction disorders have been described including BNC2 in urethral stenosis (Kolvenbach et al., 2019); FLNA in syndromic urethral anomalies (Wade et al., 2021); HPSE2 and LRIG2 in urofacial syndrome (Daly et al., 2010; Stuart et al., 2008); CHRM3 in prune-belly like syndrome (Weber et al., 2011); and MYOCD in megabladder (Houweling et al., 2011).