The 2016 revision to World Health Organization classification of B-lymphoblastic leukemia/lymphoma has classified BCR-ABL1, KMT2A rearrangement, ETV6-RUNX1, IL3-IGH, TCF3-PBX1, and Ph-like fusions as separate BCP-ALL subtypes [2]. Here, TCF3 is linked to acute lymphoblastic leukemia.