In addition, a Cox univariate regression model was constructed based on the DSS and PFI data of ccRCC patients, in which we further confirmed that SLC22A8 expression was an independent prognostic factor for DSS (P < .001) and PFI (P = .001) in ccRCC patients (Tables S1 and S2, Supplemental Digital Content, http://links.lww.com/MD/H121). The gene discussed is SLC22A8; the disease is nonpapillary renal cell carcinoma.