SLC22A8 and cancer: In the correlation analysis between SLC22A8 and the cancer-immune cycle, only cancer cell antigen release (step 1), cancer cell antigen expression (step 2), initiation and activation (step 3), immune cell trafficking to the tumor (step 4) (Th22 cell recruitment, monocyte recruitment, B-cell recruitment and MDSC recruitment), and recognition of cancer cells by T cells (step 6) were negatively correlated and not significantly correlated with the remaining steps (Fig. 7D).