There was no significant correlation between SLC22A8 expression and the enrichment scores of immunotherapy prediction pathways, except for alcoholism, base excision repair, microRNAs in cancer, pyrimidine metabolism, and cytokine–cytokine receptor interaction, which were all negatively correlated with the enrichment scores of immunotherapy prediction pathways (Fig. 7C). The gene discussed is SLC22A8; the disease is cancer.