Lei and colleagues pointed out that high SOX9 expression have important effects on angiogenesis and are closely related to the poor prognosis of patients with GC.[29] De Lin et al reported that SOX9 expression correlates with microvascular density, progress and prognosis in GC patients.[55] Ren et al[56] once shown that suppression of Wnt signaling pathway by PPARγ could inhibit its target SOX9 expression in GC cells. Here, PPARG is linked to gastric cancer.