TFAP2B and lung cancer: While AP2β showed both cytoplasmic and nuclear staining in most lung cancer tissues Fig. 7B, AP2β was undetectable (scored as 0) in 30.9% (47/155), while AP2β levels in 46.1% (70/155), 15.8% (24/155), and 7.2% (11/155) of cancer tissues were scored as 1+, 2+, and 3+ respectively.