With respect to malignancies, AnxA2 is expressed abundantly in various types of tumours where it is described to play a critical role in epithelial-mesenchymal transition [62, 63], cytoskeleton dynamics and tumour cell motility [64, 65], to regulate cell cycle and proliferation [66, 67] and to promote tumour angiogenesis [68, 69]. Here, ANXA2 is linked to neoplasm.