In our published studies, we also confirmed that ANGPTL3 can affect the expression levels of podocyte lipid raft-associated molecules such as nephrin and ACTN4 in an adriamycin-induced nephropathy model and can then aggravate the cytoskeleton rearrangement and cell motility of podocytes [15, 21]. The gene discussed is ANGPTL3; the disease is Nephropathy.