This same cluster, in the DMD samples only, expressed other immune-modulatory and/or profibrotic genes, such as SPP1, expressed exclusively in Mac 455,56 and TGFB57 as well as proinflammatory genes, including CD64/FCGRA and CD64b/FCGR1b48,58 (Supplementary Data 9). Here, SPP1 is linked to Duchenne muscular dystrophy.