In this analysis, LSC17 scores were only predictive of survival in the KMT2A and “Other or No Fusion” (defined as not containing one of the five gene fusion classes) AML subgroups, but not predictive of survival in the RUNX1-RUNX1T1, CBFB-MYH11, NUP98, and CBFA2T3-GLIS2 subgroups (Supplementary Fig. 5). This evidence concerns the gene GLIS2 and acute myeloid leukemia.