The potential antiviral effect of the longHR2_42 peptide was explored using a chimeric VSV virus expressing a soluble enhanced green fluorescent protein (eGFP) infection reporter, where the glycoprotein of VSV was replaced with the S protein of SARS-CoV-2 with the sequence of the Wuh strain (VSV-SARS-CoV-2-Wuh). Here, ART4 is linked to infection.