Consistent with this idea, the GREAT algorithm analysis of 351 human-specific LTR7 and LTR5_Hs loci identified seven human genes (BPY2; CDY1; DAZ2; HSFY1; RPS4Y2; SRY; LMNB1) associated by the Human Phenotype Ontology database analysis (Supplementary Table S1) with phenotypes of Y-linked inheritance (HP:0001450; p = 3.92E-07); Abnormal male reproductive system physiology (HP:0012874; p = 1.65E-05); Azoospermia (HP:0000027; p = 3.87E-05); Abnormal spermatogenesis (HP:0008669; p = 5.22E-05); Functional abnormality of male internal genitalia (HP:0000025; p = 8.37E-05). Here, LMNB1 is linked to Azoospermia.