Interestingly, spinal MNs reacted most strongly to TU-induced ER stress, as both BiP and GRP75 levels in other spinal neurons (ChAT-negative) increased only very moderately (Supplementary Fig. 7c, online resource), again emphasizing the higher vulnerability of spinal MNs to ER stress. The gene discussed is HSPA9; the disease is psychosocial stress measurement.