In this study, we found that [IGFBP-7]*[TIMP-2] levels in urine were significantly increased in the CI-AKI group at 2 h and 6 h after CM injection, and the level of [IGFBP-7]*[TIMP-2] was significantly higher than that of the non-CI-AKI group at 6 h (Figure 1). The gene discussed is TIMP2; the disease is acute kidney injury.