The authors combined fluorescently labeled AC-Bacteria with fluorescently labeled OVA antigen, and in vivo experiments proved that AC-Bacteria could indeed transport OVA antigen to a large number of CD103+ migrating DCs existing around the tumor periphery, and then CD103+ DCs were transported to lymph nodes and activated large numbers of DCs in lymph nodes. This evidence concerns the gene ITGAE and neoplasm.