Further, to probe into the influences of SOX12 and miR-342-3p on AML cell growth, apoptosis, and cycle, we cotransfected miR mimics, mimics NC, SOX12 and miR inhibitors, inhibitor NC, and si-SOX12 into KG-1 and HL-60 cells, respectively. The gene discussed is SOX12; the disease is acute myeloid leukemia.