NFE2L2 and diabetes mellitus: The inhibition of DNMT-1 during diabetes-associated myocardial I/R injury was shown to alleviate ferroptosis via NCOA4-mediated ferritinophagy [74], whereas Naringenin (a flavonoid) was reported to reduce ferroptosis and myocardial I/R injury through a nuclear factor-erythroid factor 2-related factor 2 (Nrf2)/System xc−/GPX4 regulatory axis [75].