On the contrary, the expression of YTHDF2 was lower in renal tumors including kidney chromophobe carcinoma (KICH) and renal papillary cell carcinoma (KIRP), brain lower grade glioma (LGG) and thyroid carcinoma (THCA), than that in the adjacent non-tumorous tissues. The gene discussed is YTHDF2; the disease is papillary renal cell carcinoma.