CDK4 and acute myeloid leukemia: Other CDK6 PROTACs designed for selective degradation of CDK6 over CDK4 using CDK inhibitors and CRBN ligands include BSJ-03-123 (Supplementary Table S1) (against AML) (Brand et al., 2019) and CP-10 (Supplementary Table S1) (most potent degrader from a CDK6 degrader library) which not only degraded mutated CDK6 that underwent overexpression, but also inhibited hematopoietic malignant cell proliferation (Su et al., 2019).