Another preclinical study reported the synergistic effect of tucidinostat and radiotherapy in inducing cell apoptosis and suppressing cancer stemness through regulating mir375- Eukaryotic translation initiation factor 4 gamma 3 (EIF4G3) axis in lung squamous cell carcinomas (Huang et al., 2021). Here, EIF4G3 is linked to squamous cell lung carcinoma.