Here, HCT116 cells in untreated TME (TME control) showed a distinct, luminescent immunolabeling (Figure 2A, exemplary marked with white arrows) as a sign of high, inflammation-induced NF-κB phosphorylation and nuclear translocation in the majority of CRC cells (Figures 2A,B) and confirmatory, this expression was similar to TME-HCT116 cells treated with β1-SO (0.5 μM) or β1-ASO (0.5 μM) alone. This evidence concerns the gene NFKB1 and colorectal carcinoma.