NFKB1 and colorectal carcinoma: However, when β1-ASO (0.1, 0.2, 0.5 μM) was added to resveratrol-treated TME cultures for the purpose of β1-integrin knockdown, a concentration-dependent increase of phosphorylation and nuclear translocation of NF-κB was found in CRC cell nuclei, due to the gradual removal of resveratrol’s effect (Figures 2A,B).