CEACAM5 and colorectal carcinoma: Specifically for colorectal carcinoma, α1-integrin has already been shown to be associated with increased tumorigenesis, CRC cell migration and invasion (Li et al., 2020), and β6-integrin provided even more accurate prognosis than the already established tumor marker carcinoembryonic antigen (CEA) for tumor surveillance of patients with advanced CRC stage (Bengs et al., 2019).