METTL3 mediates m6A modification to upregulate the expression of lincRNA 958 (LINC00958), which promotes HCC production and development by binding to miRNA 3619-5p (miR-3619-5p) to upregulate the expression of HCC growth factor (HDGF) (Zuo et al., 2020). This evidence concerns the gene METTL3 and hepatocellular carcinoma.