METTL3 is highly expressed in HCC, METTL3 regulates RNA expression in HCC in an m6A-dependent manner and is independent of recurrence-free survival (RFS) as a prognostic factor, promoting HCC cell proliferation, colony formation, migration, and tumorigenicity in vitro (Supplementary Table S1) (Liu et al., 2020d; Qu et al., 2020). Here, METTL3 is linked to hepatocellular carcinoma.