QTc: corrected QT, TIPS: Transjugular intrahepatic portosystemic shunt, CCM: Cirrhotic cardiomyopathy, BDL: Bile duct ligated, SHRSP rats: Stroke prone spontaneously hypertensive rats,  AT 1: Angiotensin II type 1, TGF-beta: Tumor necrosis factor –beta, ECM: Extracellular matrix. The gene discussed is LTA; the disease is Stroke.