BDL: Bile duct ligation, TNF-alpha: Tumor necrosis factor alpha, AEA: Cardiac anandamide, CB1 receptor: Cannabinoid receptor, CCM: Cirrhotic cardiomyopathy, MAP: Mean arterial pressure, CO: Cardiac output, HRS: Hepatorenal syndrome, HR: Heart rate, bpm: beats per minute, EF: Ejection fraction, CI: Cardiac index, NOS: Nitric oxide synthase. This evidence concerns the gene NOS2 and hepatorenal syndrome.