Adipoq, which was the target gene of 8 DE-lncRNAs such as MSTRG.15507.1 and MSTRG.22291.30, played a role of renal protective agent by inhibiting renal inflammation, oxidative stress, reducing albuminuria and kidney fibrosis as an endogenous bioactive polypeptide or protein secreted by adipocytes in DCA + Ang II-induced CKD mice [22, 23]. The gene discussed is AGT; the disease is chronic kidney disease.