SPDL1 and coronary artery disorder: To the best of our knowledge, there is no report of an increase in sPD-L1 levels in CAD patients; only in the course of this study did we read a recent report in which the median serum level of sPD-L1 in ACS patients was 188.7 (111.0–260.8) pg/ml and the increase in sPD-L1 levels was associated with ACS (34), which was consistent with our results.