Consistent with former studies, several amino acid transporters were also found to be highly expressed in PC tumor tissues to satisfy the increased need for proliferation (Figure 3B), such as cytoplasmic aspartate transaminase (GOT1) (34), proline oxidase (PRODH1) (35), and glutamine fructose 6-phosphate amidotransferase-1 (GFPT1) (36–38). This evidence concerns the gene PRODH and pachyonychia congenita.