The most upregulated genes in these glioma cells were metalloproteinase (MMP)-12, MMP-9, collagen type IV, α3 (COL4-A3), and CXC-chemokine ligand 9 (CXCL9), while laminin α1 (LAMA1), integrin β2 (ITGB2), MMP-1, and hyaluronan synthase 1 (HAS1) were downregulated after Bevacizumab treatment. The gene discussed is HAS1; the disease is glioma.