Due to the frontier position at present about the clinical research on the correlation between PYCR1 expression level and cancer prognosis, we only observed the prognostic value in five types of cancers (non-small cell lung cancer, gastric cancer, pancreatic ductal adenocarcinoma, hepatocellular carcinoma, and renal cell carcinoma), while the value in other types of cancers was still unclear yet. Here, PYCR1 is linked to hepatocellular carcinoma.