The study found that DNMT1 (Catalytic enzymes involved in the transfer of methyl groups in DNA to specific CpG structures) by mediating the low expression of the tumor suppressor mechanism of h samir-124 3p, targeting its related gene BCAT1, promotes esophagus squamous cells, including the reproduction, spread and invasion of cancer cells (50). Here, DNMT1 is linked to neoplasm.