TGFβ3 was also a poor prognostic factor for STAD in this study, however, compared to the large amount of data available for TGFβ1, there is a lack of relevant data demonstrating the pathogenic role of TGFβ3 in tumorigenesis, so this study is an important addition to the role of TGFβ3 molecules in gastric cancer. This evidence concerns the gene TGFB1 and gastric adenocarcinoma.