Further, NSCLC samples with high TREM2+ TAMs exhibited an increase in transforming growth factor-β-expressing FOXP3+ Tregs by flow cytometry (33), and TREM2+CD163+ macrophages were found to colocalize with FOXP3+ Tregs within HCC tumors (27). The gene discussed is TREM2; the disease is non-small cell lung carcinoma.