AKT1 and type 2 diabetes mellitus: As showed in Fig. 4, the expression level of PI3K, Akt and glycogen synthase (GS) in liver tissue of T2DM group (G2) was decreased by 66.01% (P < 0.05, by ANOVA), 71.02% (P < 0.05, by ANOVA), 42.69% (P < 0.05, by ANOVA) compared with G1, respectively.