On the one hand, microglia suppress post-stroke inflammation by producing anti-inflammatory cytokines (IL-10, transforming growth factor β) and the neurotrophic factor IGF-1, removing cellular debris by phagocytosis and suppressing astrocyte activation, thus promoting angiogenesis and tissue re-organization (Lalancette-Hebert et al., 2007; Kawabori et al., 2015; Otxoa-de-Amezaga et al., 2019). The gene discussed is IL10; the disease is stroke disorder.