Since our data suggest that Lyl1 expression is host-regulated, with no difference in mycobacterial uptake between both groups (4 hours post infection), it was interesting to observe a significantly increased bacterial burden in Lyl1-deficient BMDM when compared to wild-type BMDM in unstimulated and LPS pre-stimulated conditions at 3 and 6 days post-infection (Figure 3A). Here, LYL1 is linked to infection.