To gain insight into the immune-related processes of MS4A6A independent of glioma WHO grade, enrichment analysis of MS4A6A in LGG and GBM was conducted separately; in both glioma subgroups, immune-associated processes, such as myeloid leukocyte activation, were enriched in the MS4A6A high expression group. The gene discussed is MS4A6A; the disease is glioma.